Sanjay Mallya, BDS, MDS, PhD
Affiliated Investigator, Center for Molecular Medicine
Assitant Professor, Dept. of Oral Health and Diagnosstic Sciences

Biographical Sketch
Email: mallya@nso2.uchc.edu
Phone: 860-679-1256
Fax: 860-679-1291

 

Research Interests
The major focus of my laboratory is the study of the molecular mechanisms of oral neoplastic progression. Using transgenic animal models of oral premalignancy, we are studying the interaction between genetic and environmental factors in the development of oral squamous cell carcinoma, and the molecular and genetic events that occur during the multi-step progression of these neoplasms.

A second area of research is an investigation of the mechanisms that underlie the effects of parathyroid hormone on bone. It is well established that PTH has both catabolic and anabolic effects on bone. However, the molecular bases for these effects are poorly understood. To better understand the mechanisms that underlie these differential effects of PTH, we have embarked on studies using a transgenic mouse model of hyperparathyroidism. We are presently investigating the effects of PTH excess on cancellous and cortical bone mass architecture using molecular, histomorphometric and imaging-based approaches.

 

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